Cancer Immunotherapy: Immune Suppression and Tumor Growth

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Contenidos del Libro:

PART I: Principles of Cancer Immunobiology
1. Introduction
2. Cancer Immunoediting: From Immune Surveillance to Immune Escape
3. Immunosurveillance: Innate and Adaptive Antitumor Immunity
4. Cytokine Regulation of Immune Tolerance to Tumors
5. Immunological Sculpting: Natural Killer Cell Receptors and Ligands
6. Immune Escape: Immunosuppressive Networks

PART II: Cancer Therapeutics
7. Cytotoxic Chemotherapy in Clinical Treatment of Cancer
8. Targeted Therapeutics in Cancer Treatment
9. Concepts in Pharmacology and Toxicology
10. Cancer Immunotherapy: Challenges and Opportunities
11. Cancer Vaccines

PART III: Targets and Tactics to Improve Cancer Immunotherapy by Defeating Immune Suppression
12. Immunotherapy and Cancer Therapeutics: Why Partner?
13. Immune Stimulatory Features of Classical Chemotherapy
14. Dendritic Cells and Coregulatory Signals: Immune Checkpoint Blockade to Stimulate Immunotherapy
15. Regulatory T Cells in Tumor Immunity: Role of Toll-Like Receptors
16. Tumor-Associated Macrophages in Cancer Growth and Progression
17. Tumor-Associated Myeloid-Derived Suppressor Cells
18. Programmed Death Ligand-1 and Galectin-1: Pieces in the Puzzle of Tumor-Immune Escape
19. Indoleamine 2,3-Dioxygenase in Immune Escape: Regulation and Therapeutic Inhibition
20. Arginase, Nitric Oxide Synthase, and Novel Inhibitors of L-Arginine Metabolism in Immune Modulation

Harrison's Manual of Oncology - Bruce A. Chabner, Thomas J. Lynch, Jr., Dan L. Longo

Description:

Harrison's Manual of Oncology - Bruce A. Chabner, Thomas J. Lynch, Jr., Dan L. Longo. Our intent in writing this book is to provide a concise, straightforward, and well-referenced manual about cancer chemotherapy and biotherapy and to place in context the role of such drugs in the treatment of specific malignant diseases. Further, we offer a condensed version in PDA form for rapid reference on the ward and in the clinic. As physicians actively involved in teaching and patient care, we appreciate the challenge of providing a readily digestible resource for young physicians confronted with a patient with a challenging disease and potentially fatal disease. From today's leading clinicians in cancer care comes this comprehensive yet portable guide to the major chemotherapeutic and supportive care agents in oncology. Full of never-before-published content, this invaluable clinical companion features numerous tables and a concise, outline-oriented text, making it ideal for reference at a glance.

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