Cancer Immunotherapy: Immune Suppression and Tumor Growth

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Contenidos del Libro:

PART I: Principles of Cancer Immunobiology
1. Introduction
2. Cancer Immunoediting: From Immune Surveillance to Immune Escape
3. Immunosurveillance: Innate and Adaptive Antitumor Immunity
4. Cytokine Regulation of Immune Tolerance to Tumors
5. Immunological Sculpting: Natural Killer Cell Receptors and Ligands
6. Immune Escape: Immunosuppressive Networks

PART II: Cancer Therapeutics
7. Cytotoxic Chemotherapy in Clinical Treatment of Cancer
8. Targeted Therapeutics in Cancer Treatment
9. Concepts in Pharmacology and Toxicology
10. Cancer Immunotherapy: Challenges and Opportunities
11. Cancer Vaccines

PART III: Targets and Tactics to Improve Cancer Immunotherapy by Defeating Immune Suppression
12. Immunotherapy and Cancer Therapeutics: Why Partner?
13. Immune Stimulatory Features of Classical Chemotherapy
14. Dendritic Cells and Coregulatory Signals: Immune Checkpoint Blockade to Stimulate Immunotherapy
15. Regulatory T Cells in Tumor Immunity: Role of Toll-Like Receptors
16. Tumor-Associated Macrophages in Cancer Growth and Progression
17. Tumor-Associated Myeloid-Derived Suppressor Cells
18. Programmed Death Ligand-1 and Galectin-1: Pieces in the Puzzle of Tumor-Immune Escape
19. Indoleamine 2,3-Dioxygenase in Immune Escape: Regulation and Therapeutic Inhibition
20. Arginase, Nitric Oxide Synthase, and Novel Inhibitors of L-Arginine Metabolism in Immune Modulation